Estimating Gestational Age From Maternal-Fetal Heart Rate Coupling Parameters

Maternal and fetal heartbeat couplings are evident throughout development. Most of the published work, however, did not consider maternal physiological factors such as Heart Rate Variability (HRV), investigate interrelationships maternal-fetal coupling parameters. The aims this study to whether: 1) (HR) ( $\lambda $ -based) parameters associated with development, 2) gold standard Gestational Age (GA) can be estimated using HR variability various recording lengths. considered Electrocardiogram (ECG) signals from 60 healthy pregnant women no records abnormalities. HRV at Maternal:Fetal ratios were calculated, stepwise regression was utilized create generalized linear models considering lengths recorded (1 5 min) produce a robust estimate age. Cross-validation performances evaluated by mean square root average squared errors (mRMSE) between age values proposed GA identified Crown-Rump Length (CRL). Effect Fetal Behavioral States (FBSes) on different examine highly nonstationary nature signals. We found that strength for specific ratio is constant gestation. Results showed 2:3 2:4 common models. value [2:3] positively correlated GA, while [2:4] had negative correlation. Compared CRL, model resulted in mRMSE 2.67 3.69 weeks recordings 1 min, respectively. However, when FBS considered, both produced lower estimation errors. more reliably multivariate incorporating min ECG